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مقاله
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Abstract
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Title:
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Retinal NFL thickness changes after intravitreal Bevacizumab with and without anterior chamber paracentesis
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Author(s):
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Montahai T.MD; Valizadeh M.MD; Ramezani A, MD; Soheilian M.MD.
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Presentation Type:
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Poster
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Talieh Montahai
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Affiliation :(optional)
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E mail:
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t_montahai@yahoo.com
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Phone:
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Mobile:
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09125274078
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Purpose:
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Comparison of retinal nerve fiber layer (NFL) thickness changes following Intravitreal bevacizumab with and without anterior chamber paracentesis.
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Methods:
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In this randomized clinical trial, 90 eyes from 90 eligible patient with mild to moderate diabetic retinopathy with CSME (55 eyes) and wet type ARMD (35eyes )over 50 year were enrolled. Complete ophthalmic examination , fluorescein angiography and macular and peripapillary SD- OCT were done.Patients were randomly enrolled in one of the following groups: group A: 1.25 mg intravitreal bevacizumab injected in conventional method. Group B: 1.25 mg intravitreal bevacizumab injection following 0.1 cc anterior chamber paracentesis. IOP was checked within 2 min, 30 min, 24 hours and 3 month after injection. Peripapillary SD-OCT was repeated after 3month.
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Results:
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Mean age of participants was 66.4± 4.9 years old. Mean baseline peripapillary nerve fiber layer thickness was 85.3± 5.6 µm in group A and 85.6± 5µm in group B. Mean peripapillary NFL thickness changes after 3 month was -2± 2(P= .000) in group A and 0± 2( P= .101) in group B, that was not statistically significant.
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Conclusion:
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Conventionally intravitreal bevacizumab was not associated with significant nerve fiber layer thickness change after 3 months follow up.
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Attachment:
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