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مقاله
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Abstract
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Title:
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Systemic propranolol for periorbital and orbital capillary hemangioma
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Author(s):
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Seyed Zia Tabatabayi, Mohammad Taher Rajabi, Bahram Eshraghi, Gholamreza Jamshidi, Pasha Anvari
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Presentation Type:
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Poster
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Subject:
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Ophthalmic Plastic and Reconstructive Surgery
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Others:
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Presenting Author:
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Name:
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Pasha Anvari
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Affiliation :(optional)
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Farabi Eye Hospital, Tehran University of Medical Sciences,
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E mail:
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panvari@student.tums.ac.ir
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Phone:
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88010558
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Mobile:
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09122490767
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Purpose:
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To assess the efficacy and safety of systemic propranolol for periorbital and orbital capillary hemangioma
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Methods:
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Participants: Newly diagnosed cases of periocular capillary hemangioma in children aged up to 24 months.
All patients were treated by oral propranolol at a starting dose of 0.5 mg/kg/day, which was gradually increased up to two mg/kg/day. The treatment was continued for six months for local lesions and for eight months for diffuse lesions. Follow-up was continued for one year. Parents were asked to report possible side effects at each visit.
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Results:
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Thirty-two patients (7 males, 25 females) with a mean age of 4.5 months (range: 1.5 to 18 month) were included. Five patients had periorbital lesions extending into orbital space as documented by orbital CT or MRI. Sixteen patients (50%) showed excellent response to the therapy (defined as a decrease greater than 75% in lesion size or color intensity), 15 patients (47%) demonstrated partial response (defined as 50% to 75% decrease in size or color intensity) and one patient (3%) showed no response (less than 50% reduction in size or color intensity). No significant side effect was reported.
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Conclusion:
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Oral propranolol is a safe and effective option in the treatment of periocular capillary hemangioma.
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Attachment:
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4252propo_poster.pptx
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