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مقاله
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Abstract
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Title:
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Age-related changes in corneal curvature and shape: The Shahroud Eye Cohort Study
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Author(s):
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Hassan Hashemi MD1; Soheila Asgari MSc1; Mohammad Hassan Emamian MD, PhD2; Shiva Mehravaran MD, MIH1; Akbar Fotouhi MD, PhD3
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Hassan Hashemi
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Affiliation :(optional)
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Noor Eye Hospital
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E mail:
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info@irsocongress.org
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Phone:
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02182400
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Mobile:
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09121127421
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Purpose:
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To determine 5-year changes in corneal curvature and asphericity in the population-based Shahroud Eye Cohort Study of 40-64 year olds in Iran.
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Methods:
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Using data from the first and second phases of 3749 people, we extracted Pentacam variables including maximum and minimum simulated keratometry readings (Kmax and Kmin), mean radius of sagittal curvature (MRSC) in the central 3mm, and 2mm rings between 3-11mm from the center, and the anterior and posterior asphericity. In the analysis, repeated measures analysis of variance was used with a significance level of 0.5.
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Results:
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During the 5-year period of this survey, Kmax and Kmin increased by 0.38±1.95 D and 0.46±1.97 D, respectively. According to MRSC indices, the cornea steepened in the center up to the 5-7mm ring and flattened in the periphery. The increase in anterior and posterior asphericity was 0.15±0.14 and 0.09±0.14, respectively (all P<0.001). Women, compared to men, showed more change in Kmax, Kmin, and posterior asphericity (all P<0.001) but not in anterior asphericity (P=0.937).
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Conclusion:
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In 40-64 year olds, changes are in line with maintaining a prolate ellipsoid shape for the cornea. The corneal surface undergoes greater changes in women than in men. The anterior surface changes more than the posterior.
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Attachment:
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