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مقاله
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Abstract
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Title:
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Conventional pan-retinal photocoagulation versus extended targeted retinal photocoagulation: Efficacy in proliferative diabetic retinopathy regression
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Author(s):
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Masoud Soheilian, Homayoun Nikkhah, Alireza Ramezani, Mohammad Ghazi
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Presentation Type:
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Oral
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Homayoun Nikkhah
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Affiliation :(optional)
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Shahid Beheshti University of Medical Sceinces, Torfeh Hospital
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E mail:
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h.nikkhah52@gmail.com
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Phone:
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09123222846
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Mobile:
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09123222846
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Purpose:
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To determine efficacy of extended targeted retinal photocoagulation (ETRP) compared to classical pan-retinal photocoagulation (CPRP) in proliferative diabetic retinopathy (PDR) regression
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Methods:
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This was a single-blind randomized clinical trial. 270 eyes from 234 patients with early and high-risk PDR were assigned into two arms to receive either CPRP or ETRP, weekly in 4 sessions. Wide -field fluorescein angiography (WFFA), optical coherence tomography (OCT) and visual acuity (VA) measurements were performed before and 3 months after the last session of retinal photocoagulation. Primary and secondary outcome measures at 3 months post-laser were regression of retinal neovascularization on WFFA and central macular thickness and VA changes on OCT and e-chart respectively.
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Results:
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At 3 months, difference in PDR regression was statistically insignificant between treatment arms (CPRP 64.4%, ETRP 71.9%, p=0.19). No significant differences in VA loss (CPRP 0.07 log MAR, p=0.009; ETRP 0.09 log MAR, p<0.000) or macular thickening (CPRP 33.31μ, p<0.000; ETRP 41.08μ, p<0.000) developed between groups (p=0.76 and 0.40 respectively).
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Conclusion:
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: ETRP is at least as effective as CPRP in terms of PDR regression. Since the number of high-risk PDR eyes was greater in the ETRP group, this may indicate the greater effectiveness of this type of treatment.
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Attachment:
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