To determine the role of Interactive Binocular Treatment (I-BiTTM) in amblyopia therapy as a complementary method with patching in amblyopic children.

In this randomized clinical trial study, 50 amblyopic children (≤10 years old) with either BCVA≤20/30 or difference of≥2 lines and angle of deviation≤10pd were included. They were randomly selected in cases and controls (n=25 in each). Patching was recommended in both groups, cases were also received I-BiTTM. VA and stereoacuity was tested at baseline, one month at the end of treatment and one month post-treatment. The child was asked to play with games designing in I-BiTTM system, 20-30 minutes in each session for 5 days in each week.

Among 50 amblyopic children (25females and 25males) with the BCVA of 0.33±0.15LogMAR and age of 5.67±1.88 years old. Although changes were significant in both groups (0.17±0.69 and 0.05±0.07 in cases and controls, respectively), it was more in cases (p<0.001). There were no cases with the recurrence of amblyopia one month after cessation of treatment, but the rate of BCVA improvement was slower. Most cases achieved central stereopsis after treatment.

I-BiTTM is suggested as an effective accompanying method with patching to shorten the duration of amblyopia treatment and attract cooperation of children.