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مقاله
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Abstract
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Title:
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Confocal Microscopy in Management of Fungal Keratitis
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Author(s):
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Mohammad Soleimani, Seyed Ali Tabatabaei, Mehdi Tabatabaei
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Mohammad Soleimani
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Affiliation :(optional)
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TUMS
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E mail:
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soleimani_md@yahoo.com
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Phone:
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88647168
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Mobile:
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09121096496
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Purpose:
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To report clinical and imaging parameters during the course of fungal keratitis
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Methods:
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A series of 17 consecutive patients with proven fungal keratitis by culture was followed with weekly In Vivo Confocal Microscopy (IVCM). Visual acuity, diameter of infiltration, filamentous density and slit photography were recorded.
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Results:
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There were 15 male and 2 female patients. Mean age was 44.5 years (range 17-58), 10 out of 17 (58%) cultures were Fusarium, 5 (29%) were Aspergillus, 1(5%) was candida and 1(5%) was Pseudallescheria boydii. Visual acuity was HM to 20/40 and the mean diameter of infiltration was 3.2 mm (range 1-6) at the time of diagnosis. The density of infiltration showed positive relationship for non-responsiveness. The density of filamentous and bifurcations significantly reduced during the treatment of responsive of fungal keratitis in IVCM. Branching pattern of hyphae was different between different types of fungal keratitis. The mean time for IVCM becoming clear of hyphae was 41 days.
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Conclusion:
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IVCM is a valuable tool for diagnosing fungal keratitis. Density of the corneal infiltration (Not the diameter of infiltration) can be a prognostic factor. The treatment could be safely monitored by IVCM according to the density of filamentous and bifurcations .
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Attachment:
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