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مقاله
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Abstract
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Title:
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Keratoconus diagnosis using Corvis ST measured biomechanical parameters
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Author(s):
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Roghayeh Elham, Ebrahim Jafarzadepur, Kazem Amanzade, Mehdi kabazkhoob
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Roghayeh Elham
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Affiliation :(optional)
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1.Department of Optometry, Iran University of Medical Sciences 2.Noor Eye Hospital
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E mail:
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elham447@yahoo.com
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Phone:
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Mobile:
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09122398395
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Purpose:
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To assess the diagnostic power of the Corvis ST (CST: Corneal Visualization Scheimpflug Technology) provided corneal biomechanical parameters in keratoconic corneas.
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Methods:
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Corvis provided corneal biomechanical parameters of 48 eyes with mild to moderate keratoconus were compared with the corresponding ones in 50 normal eyes. The parameters predictive ability was assessed by ROC curves. To control the effect of central corneal thickness (CCT) difference between two groups, two subgroups with similar CCT were selected and the analyses were repeated.
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Results:
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Of the 10 parameters compared, means of the 8 were significantly different between two groups. ROC curve analyses showed excellent distinguishing ability for applanation-1 time (A1T) and highest concavity radius (HCR) (AUC > 0.9), and good distinguishing ability for applanation-2 time (A2T), applanation-2 velocity (A2V), and deformation amplitude (HCDA) (0.9 > AUC > 0.7). A1T reading was able to correctly identify at least 93% of eyes with keratoconus (cutoff point 7.03). In two CCT matched subgroups A1T showed an excellent distinguishing ability again.
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Conclusion:
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The A1T seems a valuable parameter in the diagnosis of keratoconic corneas. It showed excellent diagnostic ability even when controlled for CCT. Diagnostic capacity of Corvis parameters needs to be explored more.
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Attachment:
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