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مقاله
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Abstract
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Title:
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Pattern of Macular Ganglion cell-Inner Plexiform Layer Defect in Anterior Ischemic Optic Neuropathies compared to Open-Angle Glaucoma
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Author(s):
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Masoud Aghsaei Fard, Marjan Afzali, Sasan Moghimi
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Presentation Type:
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Poster
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Subject:
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Strabismus & Neuro-ophthalmology
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Others:
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Presenting Author:
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Name:
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Masood Aghsaie fard
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Affiliation :(optional)
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Farabi Eye Hospital
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E mail:
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masood219@gmail.com
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Phone:
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4794177
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Mobile:
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09127934689
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Purpose:
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To compare the pattern of macular ganglion cell inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) changes in moderate to severe primary open-angle glaucoma (POAG) with non-arteritic anterior ischemic optic neuropathies (NAION) using optical coherence tomography (OCT) auto-segmentation and to determine whether a relationship exists between structural changes and visual acuity loss.
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Methods:
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A total of 138 eyes (42 eyes with chronic unilateral NAION and their unaffected fellow eyes, 32 eyes of 32 moderate to severe glaucoma patients, and 22 eyes of 22 healthy normal subjects) were included in this study.
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Results:
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Peripapillary RNFL, total macula, and GCIPL were significantly thinner in NAION and POAG eyes compared to unaffected fellow eyes of NAION and control age-matched healthy eyes in all sectors (all P values< 0.001). There was no significant difference in peripapillary RNFL, total macula, and outer GCIPL thicknesses between the affected eyes of the patients with NAION and glaucoma patients. However, the inner GCIPL was significantly thinner in NAION compared to POAG after adjusting for age, sex, and mean deviation of the visual field. (P=0.001).
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Conclusion:
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Patients with NAION show a more decreased inner GCIPL thickness, (closer to the fovea) compared with those with POAG.
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Attachment:
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