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مقاله
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Abstract
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Title:
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Optical coherence tomography (OCT) findings of retinal nerve fiber layers (RNFL) in two common types of Multiple sclerosis
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Author(s):
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yasemi masoud,hashemzahi zabih, zare musa, azimi ali,
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Presentation Type:
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Poster
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Masoud Yasemi
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Affiliation :(optional)
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• Poostchi Eye Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
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E mail:
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masoodyasemi@yahoo.com
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Phone:
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Mobile:
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09185126077
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Purpose:
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Optical Coherence Tomography (OCT) is a non- invasive optical imaging technology, which can measure thickness of retinal nerve fiber layer as well as diameter of macula. Purpose of the study is evaluation OCT findings in two common types of multiple sclerosis .
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Methods:
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For doing the cross-sectional study, 63 patients with two prevalent types of multiple sclerosis were investigated for 6 months. Then, thickness of retinal nerve fiber layer (RNFL) as well as thickness and volume of macula were measured in the patients using OCT technology. Finally, data analysis was carried out by means of SPSS software
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Results:
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Overall, 35 patients with RRMS (with mean age (32.37+10.01), average disease period (3.81+3.42) and 28 patients with SPMS (with mean age (39.21+9.33) were assessed and were compared in terms of retinal nerve fiber layer and size and thickness of macula where In all these sections these thickness were smaller in SPMS patients than patients with RRMS. No significant correlation was found among rising disability and reduced thickness of macula and optic nervous layer.
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Conclusion:
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Based on the study results, it can be said that OCT is useful method for showing Axonal degeneration severity and evaluation of various drugs effects on course of MS disease
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Attachment:
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4214OCT and MS.pptx
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