|
مقاله
|
Abstract
|
|
|
|
Title:
|
Corneal Patch Graft: A Novel Procedure For Scleral Necrosis Secondary to Plaque Radiotherapy
|
|
Author(s):
|
Masood Naseripour 1,5, Hossein Aghaee1, Ahad Sedaghat1, Ahmad Kheirkhah2, Ramin Jaberi 3,Zohreh Azma
|
|
Presentation Type:
|
Oral
|
|
Subject:
|
Posterior Segment and Uveitis
|
|
Others:
|
|
|
Presenting Author:
|
|
|
Name:
|
Hossein Aghaee
|
|
Affiliation :(optional)
|
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
|
|
E mail:
|
aghaee.h1376@yahoo.com
|
|
Phone:
|
02166554534
|
|
Mobile:
|
09122933558
|
|
|
|
|
Purpose:
|
o evaluate the anatomical outcomes of corneal patch graft in patients with progressive scleral necrosis secondary to plaque radiotherapy used for uveal malignant melanoma management.
|
|
Methods:
|
In this case series, four patients with progressive scleral necrosis following Ru-106 plaque radiotherapy underwent corneal patch graft by anterior corneal button from DSAEK donor tissue to strengthen the sclera and to improve appearance of the eye.
|
|
Results:
|
Ciliary body involvement was evident in all cases. Four patients had received radiation doses of 400 Gy or more to the tumor base. The mean time interval between plaque radiotherapy and scleral necrosis was 24.5 ± 7.5 months (range, 18-34 months). Successful results were achieved in all patients with tectonic graft. No patients experienced graft thinning, rejection, infection, or tumor recurrence in mean follow-up of 28.5± 7.9 months (range,20-39 months).
|
|
Conclusion:
|
Corneal patch graft by anterior corneal button from DSAEK donor tissue results in successful restoration of globe integrity and satisfactory cosmetic appearance in patients with scleral necrosis secondary to plaque radiotherapy.
|
|
Attachment:
|
|
|